【摘要】 目的 探讨肺炎衣原体感染在心房颤动发病中的作用。方法 44例心房颤动患者，45例健康对照，应用间接微量免疫荧光法测定血清肺炎衣原体特异性IgG、IgM抗体滴度。结果 对照组与心房颤动患者肺炎衣原体总感染率分别为42%和87%，其中既往感染率分别为42%和70%，急性感染率分别为0和18%。心房颤动患者肺炎衣原体感染率显著高于对照组(P=0.002)。两组患者肺炎衣原体特异性IgM抗体均为阴性。结论 心房颤动患者肺炎衣原体感染率显著高于正常对照，提示肺炎衣原体感染可能参与心房颤动的发生。

    【关键词】 心律失常；心房颤动；肺炎衣原体；微量免疫荧光

    Chlamydia pneumoniae infection in pathogenesis of atrial fibrillation

    ZHANG Xin-xia,HUANG Jian-ping,ZHANG Guo-liang,et al.Department of Cardiology,Shenzhen Futian Hospital Affiliated to Guangdong Medical College,Shenzhen 518033,China

    【Abstract】 Objective To evaluate the chlamydia pneumoniae infection in pathogenesis of atrial fibrillation.Methods Serology of chlamydia pneumoniae-specific IgG and IgM antibodies were detected by microimmunofluorescence test in 45 health controls and 44 atrial fibrillation patients.Results The total infection rates were 42% and 87%,the previous infection rates were 42% and 70%,the acute infection rates were 0 and 18%,respectively.The frequency of infection rate was significantly higher in atrial fibrillation patients than that in control subjects.The chlamydia pneumoniae-specific IgM antibodies were negative in both groups.Conclusion The frequency of infection rate was significantly high in atrial fibrillation patients.It suggests that chlamydia pneumoniae infection may take part in pathogenesis of atrial fibrillation. ......