脑卒中患者血清尿酸测定的临床意义
血清尿酸；脑卒中；自由基,,],血清尿酸；脑卒中；自由基,1对象与方法,2结果,3讨论,参考文献
[摘 要] 目的 探讨脑卒中患者血清尿酸(UA)测定的临床意义。方法 检测70例脑梗死和50例脑出血急性期患者的血清UA含量，并与100例健康成人的血清UA值作对比分析。结果 脑梗死和脑出血组患者血清UA水平高于正常对照组(P<0.001)，且随病情的加重血清UA水平呈增高趋势，与对照组比较，轻、中、重型三组脑卒中患者血清UA水平均增高(P<0.002 ~0.001)。结论 UA可作为自由基代谢的指标。脑卒中患者尤其是血清UA升高明显的重型患者，应及早应用抗自由基药物。[关键词] 血清尿酸；脑卒中；自由基
The clinical significance of serum uric acid in cerebral stroke
ZHANG Wenhua, TANG Xiyou, GUAN Zhexing, et al. The 82 Hospital of PLA, Huaian 223001, Jiangsu,China
[Abstract] Objective To investigate the clinical significance of serum uric acid (UA) level change in cerebral stroke patients. Methods Serum UA levels were determined in 70 patients with cerebral infarction and 50 patients with acute cerebral hemorrhage, and these values were compared with those of 100 healthy adults. Results The serum UA levels in cerebral infarction and cerebral hemorrhage patients were much highter than those in healthy adults (P<0.001), and serum UA levels shown increasing tendency with patients' condition worsened. There were much higher in serum UA levels among the mild, medium and heavy cerebral stroke than those in healthy adults (P<0.002~0.001).Conclusions Serum UA level is a marker as the free radical metabolism. The cerebral stroke patients whose especially are severe type cases with serum UA levels markedly increased, antifree radical drug should be early applyed. ......
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