【摘要】 目的 观察脑干梗死后全身炎症反应综合征(SIRS)的发生情况，并探讨其病因及高危因素。方法 根据116例脑干梗死住院患者的体温、心率、呼吸频率及白细胞计数确定是否存在SIRS，分析与SIRS发生相关的因素。结果 116例脑干梗死患者中，SIRS 70例，46例无SIRS。脑干梗死后SIRS的发生与脑干梗死的危重程度及基础疾病密切相关。存在SIRS的患者死亡率较无SIRS者明显升高。结论 脑干梗死后出现SIRS提示疾病仍在进展，预后较差；除脑干梗死本身的严重程度外，患者并存的躯体疾病也是激发SIRS的重要因素。

    【关键词】 脑干梗死；脓毒症综合征

    A retrospective study of systemic inflammatory response syndrome following brain stem infarction

    YUAN Yong,ZHU Ben-liang.Department of Neurology, The Second Affiliated Hospital of Xuzhou Medical School,Xuzhou 221006,China

    【Abstract】 Objective To investigate the factors which induce systemic inflammatory response syndrome(SIRS)following brain stem infarction and its prognosis of these patients.Methods We studied 116 cases of brain stem infarction retrospectively,the occurrence of SIRS was determined by the body temperature,heart rates,respiratory rates and the count of white blood cell.Results 70 patients had SIRS in total of 116 patients with brain stem infarction.The occurrence of SIRS after brain stem infarction was highly associated with the overall health conditions of the patients.Our analysis showed that the mortality of the patients with SIRS was much higher than those without SIRS.Conclusion Our study suggested that the occurrence of SIRS after brain stem infarction was an indication of further tissue damage and therefore a poor prognosis.Besides brain stem infarction itself,other diseases of the patients also play important roles in the occurrence of SIRS. ......