Impact of blastomere survival on implantation rate of frozenª²thawed embryo transfer

    LUO Yaª²Ning£¬WANG Xiaoª²Hong£¬LI Li£¬YANG Yanª²Hong£¬HUANG Jianª²Lei£¬ZHANG Yuanª²Qiang£¬ YAO Yuanª²Qing

    Department of Obstetrics and Gynecology£¬Tangdu Hospital£¬ Xi¬ðan 710038£¬China£¬Department of Histology and Embryology£¬ School of Basic Medicine, Fourth Military Medical University£¬Xi¬ðan 710033£¬China

    ¡¾Abstract¡¿ AIM: To study the impact of blastomere survival on the implantation rate of frozenª²thawed embryo transfer (FET). METHODS£ºWe conducted a retrospective analysis of 134 FET cycles from September 2003 to September 2005. According to blastomere survival rates, all FET cycles were categorized into 3 groups: group A (n=46) included cycles in which all their original blastomeres remained intact£»group B (n=65) refered to mixed transfer of fully intact embryos together with partially damaged ones£»group C (n=23) was composed of all transferred embryos with partially damaged blastomere. RESULTS: Out of 642 thawed embryos, 455 survived, survival rate being 70.8%. The pregnancy rate was 24.6% per FET cycle. The pregnancy rate and the implantation rate of group A, B,and C were respectively 34.7% and 18.5%, 23.1% and 8.2%, 8.7% and 3.8%. There was a significantly higher implantation rate in group A than in group C(P<0.05). Along with the increase of intact embryos in FET cycles (0, 1, 2, 3), there was a significant increase in the pregnancy rate (8.7% ......