Clinical contrast study of antibacterial action by urinary catheters coated with nanometerª²silver

    ZHAO Yaª²Qun, ZHOU Jingª²An, LIU Guangª²Tao, GUO Hongª²Yan, WANG Xiaoª²Yang, ZHAO Li, CHEN Qin

    Department of Neurosurgery, Second Affiliated Hospital, PLA General Hospital, Beijing 100091, China

    ¡¾Abstract¡¿ AIM: To study the antibacterial action of urinary catheters coated with nanometerª²silver. METHODS: Catheª²terized patients in neurosurgery department were randomly divided into 2 groups£ºordinary urinary catheter group and urinary catheter coated with nanometerª²silver group. After the patients with catheterization time less than 7 d were rejected£¬ all 30 patients were studied including 17 with urinary catheter coated with nanometerª²silver and 13 with ordinary urinary catheter. Urine routine and urine culture were done before and 7, 14, 21, 28 d after urethral catheterization. The end of urinary catheters was cultured after a urinary catheter was pulled out. RESULTS: The positive number of urinary leukocytes before and 7, 14, 21, 28 d after urethral catheterization was 1, 5, 6, 8, 9, respectively for ordinary urinary catheter group,but for urinary catheter coated with nanoª²meterª²silver group it was 0, 1, 2, 4, 5, respectively (P<0.05). The positive number of urine culture before and 7, 14, 21, 28 d after urethral catheterization was 0, 3, 5, 7, 8, respectively for ordinary urinary catheter group, but for urinary catheter coated with nanometerª²silver group it was 0, 0, 1, 3, 4, respectively (P<0.05). The Escherichia coli, Pseudomonas aeruginosa, Staphylococcus aureaus, Streptococcus viridans and Proteus species were found in 3, 4, 3, 1, 2 cases respectively in urine culture for ordinaryurinary catheter group, but for urinary catheter coated with nanometerª²silver group those were found in 2, 1, 1, 1, 0 cases respectively. Those microorganisms were found in 8, 3, 4, 3, 2 cases respectively in urinary catheter culture for ordinary urinary catheter group, but for urinary catheter coated with nanometerª²silver group, they were found in 3, 1, 2, 0, 1 cases respectively (P<0.05). CONCLUSION: Catheters coated with nanometerª²silver have an antibacterial action. ......