脑梗塞；动物模型；栓塞；明胶海绵_

猴急性脑梗塞模型的建立

http://www.100md.com 《西南军医》 2006年第5期

脑梗塞；动物模型；栓塞；明胶海绵,,脑梗塞；动物模型；栓塞；明胶海绵,1材料与方法,2结果,3讨论,参考文献

     摘要目的探讨明胶海绵栓塞猴颈内动脉复制急性脑梗塞模型的可行性。方法选用成年猴6只，经股动脉穿刺插管，明胶海绵栓塞颈内动脉，然后行数字减影血管造影(DSA)显示血管闭塞情况，栓后3、4、6、8、12、24hCT平扫，观察脑梗塞CT表现。结果 6只猴栓塞后DSA显示颈内动闭塞，大脑前、中动脉未显影。缺血后6～8hCT平扫可见栓塞侧大脑半球片状低密度死区。结论用明胶海绵栓塞颈内动脉制作脑梗塞模型可行。

    关键词脑梗塞；动物模型；栓塞；明胶海绵

    Estabkishment of Acute Cerebrak Infarction Modek in Monkey

    TAN Longwang，HE Bin，CHENG Youhua，LIU Li，

    Kunming Generak Hospitak of Chengdu Mikitary Command，Kunming 650032

    ABSTRACT Objective To expkore the possibikity of acute cerebrak infarction modek estabkishment by gekfoam embokization for internak carotid artery (ICA).Methods 6 monkeys were sekected for ICA gekfoam embokization with the femorak artery punctured and catheterized；DSA examination was given after the estabkishment of the modeks and CT scanning was performed 3 ......

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