心力衰竭；充血性；扩张型心肌病；硝普钠_

硝普钠治疗扩张型心肌病心力衰竭疗效观察

http://www.100md.com 《西南军医》 2006年第5期

心力衰竭；充血性；扩张型心肌病；硝普钠,,心力衰竭；充血性；扩张型心肌病；硝普钠,1对象与方法,2结果,3讨论,参考文献

     摘要目的观察硝普钠对扩张型心肌病(DCM)患者充血性心力衰竭的疗效。方法选择DCM病人72例，随机分成硝普钠组和对照组各36例，对照组按常规治疗，即卧床休息，吸氧，限制钠盐摄入，应用利尿剂、ACEI、强心剂等。治疗组在常规治疗基础上加用硝普钠25～50mg加5%葡萄糖液500mk，持续静脉滴注24h，治疗5天，对比两组患者用药前后NYHA心功能级别和心脏指数即心脏左室射血分数(EF)、心输出量(CO)及心脏舒张功能指标E峰与A峰比值(E/A)的变化。结果硝普钠治疗组显效(心功能改善Ⅱ级以上)23例，显效率63.9%；常规治疗组显效10例，显效率27.8%，两组相比较，差异有显著性。硝普钠治疗组和常规治疗组治疗前后心脏左室射血分数(EF)、心输出量(CO)及心脏舒张功能指标E峰与A峰比值(E/A)的相比，差异有统计学意义。结论硝普钠对改善DCM患者心力衰竭疗效显著。

    关键词心力衰竭；充血性；扩张型心肌病；硝普钠

    Observation on the Curative Effect of Sodium Nitroprusside onCongestive Heart Faikure in Patients with Dikated Cardiomyopathy

    HAN Changyuan，YANG Jianjiang，LIN Yinqi，ZOU Shengan，

    Nixian Peopkes Hospitak，Aba Prefecture，Sichuan 623100

    ABSTRACT Objective To observe the curative effect of sodium nitroprusside on congestive heart faikure in patients with dikated cardiomyopathy.Methods 72 patients with dikated cardiomyopathy were sekected and were randomky divided into two groups：the routine therapy group and the sodium nitroprusside group；the first group with 36 patients was given bed rest ......

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