VX2肾移植癌_____]_兔；VX2肾移植癌；螺旋CT

兔VX2肾移植癌模型传代的改进和螺旋CT评价

http://www.100md.com 《实用医技杂志》 2006年第11期

VX2肾移植癌,,],兔；VX2肾移植癌；螺旋CT,[摘要],[关键词],1材料与方法,2结果,3讨论,参考文献：

     [摘要] 目的：用改良法建立兔VX2肾癌模型后研究其螺旋CT表现，探讨其在肾癌实验研究中的应用价值。方法：日本大白兔30只，采取VX2肿瘤悬液CT引导穿刺种植法(改良法)成瘤后行螺旋CT动态平扫及增强检查。结果：改良法植瘤后全部成瘤，螺旋CT平扫呈等密度或低密度灶，增强后呈低密度结节，边缘环形强化，3周后肿瘤均发生不同程度液化坏死而出现高低密度混合结节状。结论：改良法建造兔VX2肾移植癌模型方便且成瘤性高。兔VX2肾移植癌模型的最佳实验阶段是植瘤后2周~3周。螺旋CT检查简单、无创、安全、高效并可动态观测。

    [关键词] 兔；VX2肾移植癌；螺旋CT

    Improvement on the Passage of Rabbit VX2 Carcinoma Model and Spiral CT Evaluation

    CAI Yuhong，MAO Yunying

    (1.The Affiliated Hospital of Shanxi Medical College,Xi'an，Shanxi 710077，China;2.The Second Affiliated Hospital of Xi'an Jiaotong University,Xi'an,Shanxi 710004,China)

    Abstract：Objective To discuss the improvement on the passage of rabbit VX2 carcinoma modelin experiment and research its spiral CT examination.Methods 30 rabbits were taken tumor block transplanting guided by spiral CT to establishing the rabbit VX2 carcinoma model.The plain and dualphase enhanced spiral CT were all performed in 30 rabbit VX2 carcinoma models.Results Two weeks after tumor block transplanting guided by spiral CT,All the carcinomas were shown to be homogeneously hypointense by enhanced spiral CT.Conclusion The improved methods in the experimentis proved to be convenient andapt to establish the carcinoma model.The best stage to experiment is 23 weeks after tumor block transplanting.Spiral CT examination is easy、hurtless、safe、efficient and can be observed when necessary. ......

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