老年；抑郁障碍；临床特征_____老年；抑郁障碍；临床特征

老年期抑郁障碍患者临床特征对照分析

http://www.100md.com 《临床心身疾病杂志》 2006年第4期

老年；抑郁障碍；临床特征,,老年；抑郁障碍；临床特征,【摘要】,【关键词】,1对象与方法,2结果,3讨论,参考文献

     【摘要】 目的探讨老年期抑郁障碍患者的临床特征。方法对31例老年期抑郁障碍住院患者及31例<60a同期住院的抑郁障碍患者采用"抑郁障碍患者一般项目调查表"进行调查分析。结果研究组并发躯体疾病较多(P<0.01或0.05)；病前生活事件以躯体疾病为诱因较多(P<0.05)；焦虑、食欲下降、自责、昼重夜轻波动表现较对照组更多见，而反应慢/记忆下降较对照组少(P<0.05)；抗抑郁药物以SSRI类为主，不良反应发生率较对照组高，但差异无显著性(P>0.05)。结论老年期抑郁障碍患者多并发焦虑障碍及躯体疾病，对精神药物耐受性差，药物治疗应从小剂量开始，缓慢增加剂量，确保用药安全，提高治疗依从性及临床疗效。

    【关键词】 老年；抑郁障碍；临床特征

    Controlled analyses of the clinical features of senile patients with depressive disorder

    Qiu Yousheng，Duan Weidong，Gao Huan，et al

    (Kangning Hospital of Shenzhen, 518020,Guangdong,China )

    【Abstract】 Objective To explore the clinical features of senile patients with depressive disorder. Methods Statistic analyses were conducted with the Selfmade General Items Questionnaire of Depression in 31 senile inpatients with depressive disorder and 31 inpatients(<60 years) at the same time. Results Compared with control group, most of the senile patients complicated with somatic diseases(P<0.01 or 0.05); precipitating cause of most patients was somatic diseases(P<0.05); anxiety, anorexia, selfaccusation and fluctuating of severity on daytime and mildness on night were more common, while slow response/hypomnesis fewer(P<0.05); used antidepressants were mainly SSRIs and side effects higher, but difference had no significant(P>0.05). Conclusion Most of senile depressive patients complicate with anxiety and somatic diseases and have poorer tolerance to antipsychotics, so drugtreatment should begin with smalldose, gradually increase, ensure safety and improve compliance and clinical efficacy. ......

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