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编号:11319753
末梢血活性氧毒性物在肝癌诊断中的价值
http://www.100md.com 贾克东, 石淑仙, 阮幼冰
肝细胞癌;肝硬化;血液诊断,贾克东,石淑仙,阮幼冰,贾克东,通讯作者:,收稿日期:,接受日期:,Valuesofreactiveoxygent
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     贾克东, 江西省人民医院消化内科 江西省南昌市 330006

    石淑仙,
华中科技大学同济医学院附属同济医院传染科 湖北省武汉市 430030

    阮幼冰,
华中科技大学同济医学院超微病理室 湖北省武汉市 430030

    贾克东,
2003年华中科技大学同济医学院博士, 主任医师, 硕士研究生导师, 主要从事肝脏和消化疾病的临床医疗与研究工作.国家自然科学基金资助项目, No.30070847

    通讯作者:
贾克东, 330006, 江西省南昌市爱国路92号, 江西省人民医院消化内科. jiakedong@tom.com

    收稿日期:
2006-03-22 接受日期: 2006-05-08

    Values of reactive oxygen toxic species of finger blood dot in the diagnosis of hepatocellular carcinoma

    Ke-Dong Jia, Shu-Xian Shi, You-Bing Ruan

    Ke-Dong Jia, Department of Gastroenterology, Jiangxi Provincial People’s Hospital, Nanchang 330006, Jiangxi Province, China

    Shu-Xian Shi,
Department of Infectious Diseases, Tongji Hospital of Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China

    You-Bing Ruan,
Department of Ultrostructural Pathology, Tongji Medical College, Huazhong University of Science and Technology, Wuhan 430030, Hubei Province, China

    Supported by
National Nature Science Foundation of China, No.30070847

    Correspondence to:
Ke-Dong Jia, Department of Gastroenterology, Jiangxi Provincial People’s Hospital, 92 Aiguo Road, Nanchang 330006, Jiangxi Province, China. jiakedong@tom.com

    Received:
2006-03-22Accepted: 2006-05-08

    AbstractAIM: To observe the morphology and inclusion body of reactive oxygen toxic species (ROTS) of finger blood dot in hepatocellular carcinoma (HCC) and liver cirrhosis (LC) by multimedia microscopy and explore its value in the diagnosis of HCC.

    METHODS:
The finger blood dots were prepared from 28 patients with HCC, 43 patients with LC, 38 patients with other carcinomas. The blood dots were scanned and the morphology and inclusion body of ROTS were analyzed by high-vivid color pathology image analysis system (HPIAS-1000) between different groups of patients.

    

    RESULTS:
The enlarged ROTS was detected in 20 of 28 patients with HCC and 16 of 43 patients with LC ......

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