血清总胆汁酸在婴幼儿巨细胞病毒肝炎中的动态变化及临床意义
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刘 薇, 蒋玉红, 王亚秋, 李 伟
婴儿;巨细胞病毒肝炎;血清总胆汁酸;动态变化,刘薇,蒋玉红,王亚秋,李伟,通讯作者:,Dynamicchangesandclinicals
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刘薇, 蒋玉红, 王亚秋, 李伟, 青岛市妇女儿童医疗保健中心检验科 山东省青岛市 266011
通讯作者: 蒋玉红, 266011, 山东省青岛市武定路27号, 青岛市妇女儿童医疗保健中心检验科. jyh0532@suho.com
电话: 0532-82857535 传真: 0532-82824382
收稿日期: 2006-07-29 接受日期: 2006-08-10
Dynamic changes and clinical significance of serum total bile acid in infantile cytomegalovirus hepatitis
Wei Liu, Yu-Hong Jiang, Ya-Qiu Wang, Wei Li
Wei Liu, Yu-Hong Jiang, Ya-Qiu Wang, Wei Li,Clinical Laboratory, Qingdao Women and Children’s Medical and Health Care Center, Qingdao 266011, Shandong Province, China
Correspondence to:Yu-Hong Jiang, Clinical Laboratory, Qingdao Women and Children’s Medical and Health Care Center, 27 Wuding Road, Qingdao 266011, Shandong Province, China. jyh0532@suho.com
Received:2006-07-29 Accepted:2006-08-10
Abstract
AIM: To investigate the dynamic changes of serum total bile acid (TBA) in infantile cytome-galovirus hepatitis.
METHODS: The levels of serum TBA in 21 infants suffered cytomegalovirus hepatitis were detected dynamically (at the first visit to a doctor, before treatment in hospital, 2 wk after treatment, and at the time leaving hospital). Meanwhile, the results were comparatively analyzed with alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels.
RESULTS: Of the 21 cases, the positive rate of TBA was significantly higher than that of ALT before treatment in hospital (100%vs 80.9%, P < 0.01). The infants with TBA > 80 μmol/L had higher risk of unfavorable prognosis than those with TBA ≤ 80 μmol/L (75% vs 23 ......
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