缓释渗透增敏化疗加放疗综合治疗食管癌50例
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王志蕙, 侯海燕, 范士怀, 彭京凤
缓释渗疗器;食管癌;常规分割放疗;化疗;增敏王志蕙,侯海燕,范士怀,彭京凤.缓释渗透增敏化疗加放疗综合治疗食管癌50例. 世界华人消化杂志2006;14(26)2640-2644,缓释渗透
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王志蕙, 彭京凤, 山东省临沂市肿瘤医院 山东省临沂市 276001
侯海燕, 山东省省立医院 山东省济南市 250000
范士怀, 山东省临沂市中医医院肿瘤中心 山东省临沂市 276002
通讯作者: 王志蕙, 276001, 山东省临沂市, 山东省临沂市肿瘤医院. monica_ok_6@163.com
电话: 0539-3690518
收稿日期: 2006-05-20 接受日期: 2006-07-19
Radiosensitizing effect of extended-release chemotherapy combined with radiotherapy in treatment of esophageal cancer: an analysis of 50 cases
Zhi-Hui Wang, Hai-Yan Hou, Shi-Huai Fan, Jing-Feng Peng
Zhi-Hui Wang, Jing-Feng Peng, Linyi Tumor Hospital, Linyi 276001, Shandong Province, China
Hai-Yan Hou, Shandong Provincial Hospital, Ji’nan 250000, Shandong Province, China
Shi-Huai Fan, Research Center of Oncology, Linyi Hospital of Traditional Chinese Medicine, Linyi 276002, Shandong Province, China
Correspondence to: Zhi-Hui Wang, Linyi Tumor Hospital, Linyi 276001, Shandong Province,China. monica_ok_6@163.com
Received: 2006-05-20 Accepted: 2006-07-19
Abstract
AIM: To evaluate the effect of extended-release chemotherapy combined with conventional fractionation radiotherapy in treatment of esophageal cancer.
METHODS: A total of 100 patients with esophageal carcinoma were randomly divided into experiment group (n = 50) and control group (n = 50). The experiment group received extended-release chemotherapy combined with conventional fractionation radiotherapy (X-ray external irradiation), while the control group was treated only with conventional fractionation radiotherapy. The recent efficacy as well as the 1-, 3-, and 5-year survival rates was observed.
RESULTS: The rates for complete remission (CR), partial remission (PR), CR plus PR, non-changes (NC), and disease progression were 55.1%, 40.8%, 95.92%, 0, and 4.08% in the experiment group and 10%, 60%, 70%, 20%, and 10% in the control group, respectively; CR, CR+PR, and PR were significantly different between the two groups (P < 0 ......
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