慢性萎缩性胃炎24 h胃内pH值监测及血清胃泌素含量的意义
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袁华魏, 李雪雁, 徐鸰鸽, 张恩民
萎缩性胃炎;胃酸;胃泌素;pH值袁华魏,李雪雁,徐鸰鸽,张恩民.慢性萎缩性胃炎24h胃内pH值监测及血清胃泌素含量的意义.世界华人消化杂志2006;14(26)2649-2651,慢性萎缩性胃炎24h
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袁华魏, 徐鸰鸽, 张恩民, 大连市中心医院消化内科 辽宁省大连市 116033
李雪雁, 大连市第六人民医院 辽宁省大连市 116033
通讯作者: 袁华魏, 116033, 辽宁省大连市沙河口区西南路826号, 大连市中心医院消化内科. yhwlxy0515@hotmail.com
电话: 0411-84412001-613
收稿日期: 2006-04-24 接受日期: 2006-06-30
Significance of 24-h intragastric pH monitoring and serum concentration of gastrin in chronic atrophic gastritis
Hua-Wei Yuan, Xue-Yan Li, Ling-Ge Xu, En-Min Zhang
Hua-Wei Yuan, Xue-Yan Li, Ling-Ge Xu, En-Min Zhang, Department of Gastroenterology, Dalian Municipal Central Hospital, Dalian 116033, Liaoning Province, China
Xue-Yan Li, Dalian Sixth People’s Hospital, Dalian 116033, Liaoning Province, China
Correspondence to: Hua-Wei Yuan, Department of Gastroenterology, Dalian Municipal Central Hospital, 826 Southwest Road, Shahekou District, Dalian 116033, Liaoning Province, China. yhwlxy0515@hotmail.com
Received: 2006-04-24 Accepted: 2006-06-30
Abstract
AIM: To evaluate the clinical significance of 24-h intragastric pH monitoring and the serum concentration of gastrin in patients with chronic atrophic gastritis (CAG).
METHODS: A total of 126 patients with chronic gastritis, confirmed by endoscopy combined with pathological examination, were recruited in this study. Based on histological results, the patients were devided into 4 groups: non-atrophic gastritis, mild, moderate and severe CAG group, respectively. The 24-h intragastric pH value was monitored using mobile pH measuring apparatus. The serum concentration of gastrin was detected by enzyme-linked immunosorbent assay (ELISA), and H pylori infection was determined by rapid urease test and 14C urea breath test.
RESULTS: H pylori infection was assured in 73 patients, of which 52 cases were diagnosed with CAG ......
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