反复呼吸道感染患儿不同时期支气管黏膜纤毛结构的变化
儿童；反复呼吸道感染；支气管黏膜纤毛结构；治疗,,],儿童；反复呼吸道感染；支气管黏膜纤毛结构；治疗,1资料与方法,3讨论,[参考文献]
[摘要] 目的 研究反复呼吸道感染(RRTI)患儿急性期与恢复期支气管黏膜纤毛上皮结构的特点与变化，为临床治疗的有效性提供客观依据。方法 选择符合儿童RRTI诊断标准的患儿38例作为研究对象，分别于急性期及恢复期在纤维支气管镜下夹取支气管黏膜组织，电镜下观察纤毛上皮结构的特点并比较纤毛异常的发病率，探讨RRTI患儿治疗后纤毛的恢复情况。结果 RRTI患儿急性期支气管黏膜纤毛上皮结构异常的总发病率为81.6%(31/38)，经过正规治疗后恢复期纤毛异常的总发病率降为31.6%(12/38)，纤毛损害程度明显减轻，二者相比，差异有非常显著性(χ2＝18.98，P<0.001)。结论 RRTI患儿急性期普遍存在着支气管黏膜纤毛上皮结构的异常，且多为继发性异常及可逆性损害，故对于RRTI患儿在查找病因的同时应积极进行抗炎对症治疗，防止纤毛结构异常发展为不可逆性的损害。[关键词] 儿童；反复呼吸道感染；支气管黏膜纤毛结构；治疗
Study on change of bronchus mucosa cilia for children with recurrent respiratory tract infection in different stage
SHI Yuxia,LIU Lu,WEI Yanrong，et al.The Children’s Hospital of Urumqi,Urumqi 830002,China
[Abstract] Objective To investigate the change of bronchial mucosa cilia epithelium structure on children with recurrent respiratory tract infection in acute stage and convalescence stage.Methods Choose 38 cases of patients with RRTI as study group,respiratory ciliated cells were collected by bronchial fiberscope in acute stage and convalescence stage respectively,observe the change of cilia structure by electron microscopy and compare the incidence of cilia cylindrical epithelium structure abnormality.Results The incidence of cilia cylindrical epithelium structure abnormality in patients with RRTI was 81.6%(31/38) in acute stage and reduced to 31.6%(12/38)in recovery stage after regular treatment,there was significant difference between two groups (χ2＝18.98 ......
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