【摘要】 目的 评价乳酸加替沙星氯化钠注射液治疗呼吸系统急性感染的临床疗效及安全性。方法 急性呼吸道感染病人(包括中等的化脓性扁桃体炎、急性化脓性支气管炎、慢性支气管炎急性发作期、肺炎等)151例随机分为2组，试验组静脉滴注乳酸加替沙星氯化钠注射液400mg，qd；对照组静滴加替沙星氯化钠注射液400mg，qd，每瓶静滴时间多于30min，疗程7天。结果 呼吸系统感染患者试验组的临床痊愈率为63.2%(48/76)，有效率为92.1%(70/76)。对照组分别为65.3%(49/75)和92.0%(69/75)。两组疗效差异在统计学上无显著性(P>0.05)。结论 乳酸加替沙星氯化钠注射液治疗呼吸系统急性感染安全有效。

     【关键词】 乳酸加替沙星；注射液；氯化钠；呼吸系统；急性感染

    【Abstract】 Objective To evaluate the efficacy and safety of the gatifloxacin lactate in the treatment of the acute respiratory tract infection; Methuds 151 patients with acute inspiratory tract infection were enrolled in this study, The patients were divided randomized into the gatifloxacin lactate group or gatifloxacin group, the dose of both groups were 400 mg once daily by iv. The duration of the therapy was 7 days. Results The clinical recovery rate and the overall effective rate of the gatiflocacin lactate groups were 61.2 %(48/76) and 92.1%(70/76) , 65.3%(49/75) and 92.0%(69/75)in gatifloxacin groups, respectively. There were no statistical differences between the two groups. Conclusion The test gatifloxaxin lactate is effective drug of treating acute respiratoryt ract infection. ......