儿童反复呼吸道感染免疫干预前后IL-12、IL-13、IL-2、IL-4的变化及临床意义
反复呼吸道感染；儿童；免疫干预,,],反复呼吸道感染；儿童；免疫干预,1资料与方法,2结果,3讨论,参考
[摘要] 目的 探讨免疫干预前后儿童反复呼吸道感染的意义。方法 观察32例反复呼吸道感染儿童在免疫干预前后的变化，并对IL-12、IL-13、IL-2、IL-4的变化进行分析。结果 免疫干预后患儿的IL-12、IL-2的含量均升高(P<0.05，P<0.01)。而IL-13、IL-4的含量均降低(P<0.01，P<0.01)。临床呼吸道感染年均次数均减少。结论 免疫干预方法干预儿童反复呼吸道感染，有望增强反复呼吸道感染儿童的抗病能力，有益于儿童的生长发育和生活质量。[关键词] 反复呼吸道感染；儿童；免疫干预
Changes and clinical significance of IL-12,IL-13,IL-2,IL-4 before and after immunologic intervention to respiratory tract repeated infection in children
SUN Biaolong,YANG Liping,MA Deqing,et al.Department of Pediatrics,Qingpu Central Hospital,Shanghai 201700,China
[Abstract] Objective To discuss the significance of the immunologic intervention before and after to the respiratory tract repeated infection in children.Methods Observed 32 cases of the immunologic intervention before and after to the respiratory tract repeated infection in children,and analyzed the changes of IL-12,IL-13,IL-2,IL-4.Results After the immunologic intervention,the content of sick child’s IL-12 and IL-2 increases obviously(P<0.05,P<0.01),while the content of IL-13 and IL-4 decreases(P<0.01,P<0.01).The yearly average times of clinical respiratory tract repeated infection decrease.Conclusion The immunologic intervention method can intervene the children’s respiratory tract repeated infection effectively;and it can improve the ability of diseaseresistant for the children with respiratory tract repeated infection;and it benefits the growth and life quality for the children. ......
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