【摘 要】 目的 探讨早期机械通气支持对重型颅脑损伤治疗作用的临床意义。 方法 对52例接受机械通气的重型颅脑损伤患者资料进行回顾性分析，分析早期机械通气前后PaO2 、PaCO2 以及GCS评分变化并对潜在性呼吸衰竭早期机械通气患者的预后与呼吸衰竭后再上机者预后进行比较。 结果 重型颅脑损伤患者早期机械通气可明显提高PaO2 、降低PaCO2 ，提高GCS评分。呼吸衰竭前早期机械通气的神经恢复良好率为71.4%，呼吸衰竭后通气好转率仅为45.8%。 结论 早期机械通气可有效的改善重型颅脑损伤的低氧血症及意识的恢复，提高患者的生存质量。

    【关键词】 重型颅脑损伤;低氧血症;呼吸衰竭;机械通气;预后

    The early stage mechanical ventilation strategy on acute severe craniocerebral injury LI Bo-en，WUBin，WANG Bin.

    (Intensive Care Unit，The Central Hospital of Bengbu，Anhui233000，China)

    【Abstract】 Objective To investigate the therapeutic effect of early stage mechanical ventilation(MV)on patients with acute severe craniocerebral injury.Methods 52patients receiving MV were retrospectively analysed.The PaO2 ，PaCO2 and GCS after MV were compared with those before MV in patients receiving early stage MV.The prognosis of patients treated with early stage MV was compared with those who accepted traditional MV.Results The value of PaO2 and GCS was raised in the patients treated with early stage MV and that of PaCO2 was depressed.The rate of favorable neurological outcome was71.4%in early stage MV group and45.8%in traditional MV group.Conclusion The early stage MV has significant effect on hypoxemia and consciousness recovery in patients with acute severe craniocerebral injury. ......