扇贝多肽对实验性脑缺血大鼠缺血性半暗带Bcl22 蛋白表达的影响
扇贝多肽;缺血半暗带;蛋白质,Bcl22蛋白;大鼠,,],扇贝多肽;缺血半暗带;蛋白质，Bcl22蛋白;大鼠,扇贝多肽对实验性脑缺血大鼠缺血性半暗带Bcl22蛋白表达的影响,1材料与方法,2结果
[摘要] 目的 探讨扇贝多肽(PCF) 对大鼠脑缺血半影区内Bcl22蛋白表达的影响。方法 应用线栓法制作Wistar大鼠大脑中动脉缺血再灌注(MCAO) 模型，MCAO 模型大鼠随机分为PCF治疗组、蒸馏水组和模型组。免疫组织化学法测定脑组织缺血半影区Bcl22蛋白的表达。结果 PCF组脑缺血半影区Bcl22蛋白则呈过表达，与模型组及蒸馏水组相比差异有非常显著性(q=38.08、41.69，P<0.01)。结论 PCF能防止大鼠脑缺血后缺血半影区内神经元的凋亡。[关键词] 扇贝多肽;缺血半暗带;蛋白质，Bcl22蛋白;大鼠
Effect of polypeptides from chlamys farreri on the expression of Bcl22 proteins in the ischemic penumbra in rats after cerebral ischemia
CHEN Yuming.
Qingdao University Medical College，Qingdao 266021，China
[Abstract] Objective To study the effect of polypeptides from chlamys farreri ( PCF) on the expression of Bcl22 proteins in the ischemic penumbra in rats after cerebral ischemia.Methods Twenty-four Wistar rats were subjected to middle cerebral artery occlusion(MCAO) and reperfusion.The rats were randomly divided into three groups：MCAO model groups which were randomly divided into PCF group ......
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