平阳霉素与鱼肝油酸钠治疗肝血管瘤临床观察
平阳霉素;,鱼肝油酸钠;,肝血管瘤,,平阳霉素;,鱼肝油酸钠;,肝血管瘤,1资料与方法,2结果,3讨论,参考文献
【摘要】目的： 探讨平阳霉素碘油乳剂(PLE)与鱼肝油酸钠治疗肝血管瘤的疗效、安全性、患者的耐受程度。方法： 每组随机选择各10例肝血管瘤患者，分别用PLE及鱼肝油酸钠栓塞，观察每组患者栓塞后的临床反应及表现，比较其栓塞效果。结果： 1用PLE栓塞组，患者术后一般发热3~7d，最高达381℃，术中有肝区憋胀，轻度疼痛，术后肝区疼痛较轻，均未使用止痛针剂。随访5个月，肿瘤平均缩小70%以上。2用鱼肝油酸钠栓塞组，患者术后一般发热2~3d，最高者达38℃，术中即有肝区憋胀、巨痛，术后肝区疼痛剧烈，每个患者平均使用度冷丁200~300mg。随访5个月，肿瘤缩小72%以上。结论： 笔者认为平阳霉素与鱼肝油酸钠对血管的硬化和肝血管瘤的治疗，疗效相当。但平阳霉素栓塞术后，临床反应较轻，痛苦小，患者更容易接受。【关键词】平阳霉素; 鱼肝油酸钠; 肝血管瘤
Observed Clinical Effect on Pingyangmycin and
Sodium Morrhuate in Treating Hepatic Haemangioma
FENG Hua
The First Afiliated Hospital, Hebei North University, Zhangjiakou, 075000, Hebei China
【ABSTRACT】Objective: To investigate the curative effect, safety and tolerance of patients with hepatic haemangioma to lipiodol emulaion in pingyangmycin and sodium morrhuate repectively. Methods: 20 cases with hepatic haemangioma were observed and 10 cases of them were treated with pingyangmycin lipiodol emulaion, and 10 of them were treated with sodium morrhuate. Results: The tumor sizes in PLE group were reduced about 70% in average, and the that of sodium morrhuate treating group were reduced about 72%. Conclusion: The curative effect of pingyangmycin was as much as that of sodium morrhuate, but clinical adverse reaction for pingyangmycin was lower, and could be easily accepted by the patients. ......
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