[摘要] 目的 研究肝康合剂联合干扰素治疗慢性乙型肝炎的临床疗效。方法 选择慢性乙型肝炎的病例，应用肝康合剂联合干扰素进行治疗，以单独应用肝康合剂和单独应用干扰素治疗的患者进行对比观察，疗程均为6个月。观察患者治疗前后症状、体征的改善情况，肝功能、乙肝病毒标志物的变化情况。结果 治疗结束后治疗组与两对照组总有效率分别为94.4%和90.4%、85.0%，无统计学差异，P>0.05；在肝功能复常方面，3组亦无统计学差异，P>0.05；在HBeAg、HBV-DNA阴转方面，治疗组明显优于对照组，统计学处理差异有显著性(P<0.01或0.05)。结论 肝康合剂联合干扰素治疗慢性乙型肝炎具有较好疗效，肝康合剂能明显提高干扰素的抗乙肝病毒效果。

    [关键词] 中西医结合医学；肝康合剂；干扰素；肝炎，临床对照研究

    Gankang mixture combined inferon in treatment of chronic hepatitis B：a report of 54 cases

    JIN Tao，YOU Yun-ge，LI Qing-xiu，et al.Linli Hospital of Traditional Chinese Medicine，Changde 415200，China

    [Abstract] Objective To study the clinical curative effect of combined treatment with Gankang mixture and interferon in treating chronic hepatitis B.Methods Therapeutic group treated with Gankang mixture and interferon contrast group 1 and 2 treated only by Gankang mixture and interferon respectively;all to treat 6 months;the symptoms and signs of the three groups were observed before and after the treatment ......