旋毛虫病；兔；酶；肌酸激酶_

感染旋毛虫兔五种血清酶变化研究

http://www.100md.com 《河北北方学院学报》 2006年第1期

旋毛虫病；兔；酶；肌酸激酶,,旋毛虫病；兔；酶；肌酸激酶,1材料与方法,2结果,3讨论,参考文献

     【摘要】目的：用旋毛虫感染兔，研究旋毛虫病时肌酸激酶(CK)、醛缩酶(ALD)、丙氨酸氨基转移酶(ALT)、天门冬氨酸氨基转移酶(AST)和乳酸脱氢酶(LDH)五种血清酶的变化，为旋毛虫病血清酶的检测提供基础资料。方法：将31只实验用兔随机分成三组：轻度感染组11只，每只用灌胃法感染旋毛虫肌幼虫5×103条；重度感染组10只，每只喂入10×103条幼虫；对照组10只。感染后不同时间检测血清CK、ALD、ALT、AST和LDH活性。结果：兔旋毛虫病时五种血清酶(CK、ALD、ALT、AST和LDH)均升高，但以CK的升高程度最高，五种酶均于第3周达高峰，随后逐渐降低。在峰值时，兔血清CK的阳性率(100%)最高,其他阳性率分别ALD81%、ALT667%、AST619%和LDH524%。结论：兔旋毛虫病时，CK、ALD、ALT、AST和LDH五种血清酶尤其是CK的检测对于该病具有辅助诊断意义。

    【关键词】旋毛虫病；兔；酶；肌酸激酶

    Studies on the Changes in Five Serum Enzymes in

    Rabbits Infected with Trichinella spiralis

    LI Lihong，ZHANG Jinshun,LI Baoliang，et al

    Department of Clinical Laboratory Medicine，Hebei North University, Zhangjiakou,075000,Hebei China

    【ABSTRACT】Objective: To further study the activities of serum creatine kinase(CK)，fructosediphosphate aldolase (ALD)，alanine aminotransferase(ALT)，aspartate aminotransferase (AST)and lactate dehydrogenase (LDH) in rabbits infected with Trichinella spiralis， so as to supply useful basic data for serum enzymes examination in trichinosis.Methods: Experimental rabbits were divided into three groups randomly.11 rabbits in lightlyinfected group were inoculated by gavage with 5×103 larvae per rabbits ......

百拇医药网 http://www.100md.com/html/DirDu/2006/11/03/27/37/32.htm

您现在查看是摘要页，全文长 9199 字符。