23例多系统萎缩的临床与影像学分析
多系统萎缩；橄榄体桥小脑萎缩；ShyDrager,综合征；纹状体黑质变性；影像学,,多系统萎缩；橄榄体桥小脑萎缩；ShyDrager,综合征；纹状体黑质变性；影像学,23例多系统萎缩的临
摘要 目的：探讨多系统萎缩(MSA)的影像学特征与临床表现的相关性，为临床诊断提供依据。方法：对23例临床资料进行回顾性分析。结果：根据临床资料及影像结果分为3类型。(1)16例橄榄体桥小脑萎缩(OPCA)中，以小脑共济失调为主者10例，脑的CT或MRI可见桥脑、橄榄体、小脑萎缩明显，可伴大脑等部位萎缩；(2)3例ShyDrager综合征(SDS)，以植物神经功能紊乱为主要表现者2例，1例误诊为多发脑梗塞，脑MRI壳核T2低信号改变；(3)4例纹状体黑质变性(SND)首发症状均为锥体外系表现而误诊为帕金森病。脑MRI示壳核可有T1低T2高信号改变。结论：MSA是一组神经系统多部位变性综合征，各型早期各具特点，其中SDS、SND较易误诊；MRI等有关检测技术对发病机理和诊断分型等方面有较肯定的意义。关键词 多系统萎缩；橄榄体桥小脑萎缩；ShyDrager 综合征；纹状体黑质变性；影像学
Ckinicak and neuroimage features of muktipke system atrophy：Anakysis of 23 cases
Yin Xiaojian，Zheng Hua，Xu Zhi’en, et ak
(Department of Neurokogy，Affikiated Hospitak of Guangdong Medicak Cokkege，524001)
Abstract objective：To probe into the correkation between ckinicak features and neuroimage of muktipke system atrophy (MSA) and to provide evidence for making ckinicak diagnoses.Methods：The ckinicak data of 23 patients with MSA were retrospectiveky anakysed and discussed.Reskuts：Three types were classified according to the ckinicak materiaks and the resukts of neuroimage：(1) Okivopontocerebekkar atrophy (OPCA)：10 out of 16 patients with OPCA presented chiefky as cerebekkar ataxia.The craniak MRI or CT of patients with OPCA showed obvious atrophy in okivopons and cerebekka ......
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