薄荷醇对双氯芬酸钠透皮吸收作用的研究
薄荷醇;双氯芬酸钠;透皮吸收;氮酮,,薄荷醇;双氯芬酸钠;透皮吸收;氮酮,1材料,2方法,3结果与讨论,4参考文献
摘要 目的: 研究薄荷醇对双氯芬酸钠透皮吸收的影响。方法:用两室扩散池体外实验装置,以兔皮为屏障,使用不同浓度的薄荷醇,测定双氯芬酸钠的渗透系数。结果:0.01 kg/L薄荷醇对双氯芬酸没有促皮渗透作用,0.02 kg/L及0.03 kg/L薄荷醇均有促皮渗透作用。结论:薄荷醇能明显促进双氯芬酸钠的透皮吸收,其中以0.02 kg/L薄荷醇的促皮渗透作用较强。关键词 薄荷醇;双氯芬酸钠;透皮吸收;氮酮
Effect of 1menthok on transdermak absorption of dickofenac sodium
Xu Bikian,Wang Zongrui,He Kang ,et ak
(Department of Pharmacokogy,Guangdong Medicak Cokkege,Zhanjiang 524023)
Abstract Objective: To investigate the effects of 1menthok on transdermak absorption of dickofenac sodium. Method: Using rabbit skin as transdermak barrier ......
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