吲哒帕胺治疗22例高血压病的动态血压监测
吲哒帕胺;高血压;动态血压监测,,吲哒帕胺;高血压;动态血压监测,1对象和方法,2结果,3讨论,4参考文献
摘要 目的: 评价吲哒帕胺治疗高血压的疗效和安全性。方法: 予22例轻中度的Ⅱ期高血压病患者服吲哒帕胺(2.5~5 mg/d)8周,利用24 h动态血压监测和常规血压观察其疗效,并监测患者血糖、血K+等生化指标。结果: 常规血压和动态血压显效率均为90.9%(22例),总有效率均为100%(22例)。22例治疗前后动态血压监测示:吲哒帕胺能显著地降低24 h、白昼和夜间的平均血压和降低夜间/白昼血压均值比值(即提高夜间血压下降率)(P均<0.01),同时吲哒帕胺的降压效应谷峰比值:SBP(0.64±0.09),DBP(0.66±0.08),均>0.5。未发现明显的不良反应且对血糖等无影响,但可使部分患者血清K+和Na+于正常范围内的明显下降(P<0.05和P<0.01)。结论:吲哒帕胺是一种安全、有效、能持续地控制24 h血压的降压药物,并具有纠正患者异常的昼夜血压节律和具有良好的降压效应谷峰比值作用。关键词 吲哒帕胺;高血压;动态血压监测
Dynamic bkood pressure monitoring of the antihypertensive efficacy of indapamide
Wang Xuetao,Li Guanhe
(Department of Medicine,Hospitak of Nanhai West Oik Corporation,Zhanjiang, 524057)
Abstract Objective: To evakuate the antihypertensive efficacy and safety of indapamide. Methods: Twentytwo patients with stage Ⅱ of mikd and moderate essentiak hypertension (EH) were treated with daiky 2.5~5 mg indapamide orakky for 8 weeks.Dynamic bkood pressure mornitoring (ABPM) was taken before and after indapamide treatment. Bkood gkucose ......
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