[摘要] 目的 本文通过1例系统性红斑狼疮(systemic lupus erythematosus,SLE)死亡的法医学尸体检验与鉴定案例，对系统性红斑狼疮的病理组织学改变、临床病理及死亡原因等进行分析。方法 对SLE尸体检验后的各系统所取组织进行常规HE染色，光学显微镜观察。结果 SLE可累及多个器官,以肾、心包、肺、脑、脾和小血管为主，其他器官也可受到影响。结论 SLE本身为最主要的死因,其次为感染和心血管疾病，主要导致多系统器官(主要为肾、脑、心、肺)发生严重损害或衰竭而死亡。

    [关键词] 系统性红斑狼疮；法医学检验；临床病理

    Forensic autopsy examination of systemic lupus erythematosus and the studies of its causes of death and clinicopathology

    ZENG Xiao-feng,LIU Jian,JIN Tao,et al.The Faculty of Forensic Medicine,Kunming Medical College,Kunming 650031,China

    [Abstract] Objective To investigate the changes of pathology and histology,the clinicopathology and the causes of death due to systemic lupus erythematosus (SLE) through the analysis of a forensic autopsy examination and identification.Methods The histologies of necropsy SLE were examined by means of routine HE staining and light microscope.Results Almost all organs examined showed different degree damages,especially in kidney,pericardiac, lung,brain,spleen and vein,but other organs may were affected.Conclusion The most common death cause of SLE is SLE itself,secondly infection and cardiovascular disease.The SLE can cause serious damages or failures of many organs in human body,especially kidney,brain,heart and lung,and finally death. ......