[摘 要] 目的 应用组织追踪(TT)和组织同步成像(TSI)技术评价冠心病(CAD)左室心肌纵向收缩位移和同步化运动的特点。方法 应用TT和TSI获取20例CAD患者和26例正常人的左室心尖长轴、心尖二腔和心尖四腔切面，测定并比较左室长轴方向不同室壁节段的收缩期最大位移(Ds)和收缩期正向达峰时间(Ts)。结果 CAD患者TT和TSI检出的心肌异常节段与冠脉造影证实或心肌梗死的病变部位基本一致；CAD患者的Ds较正常组明显降低(P<005或P<001)，Ts测值延长，各节段之间的Ts均值差异增大(7148～18200ms，P<005或P<0001)；以基底段Ds<9mm，中间段<5mm和Ts>180ms为异常室壁节段的标准，其准确性分别为6200%和5417%，敏感性为5263%和3944%，特异性为7442%和7551%。结论 TT和TSI能较好地评价CAD患者左室心肌纵向收缩时的位移变化和同步化。

    [关键词] 组织追踪；组织同步成像；冠心病；左心室

    Quantitative study on displacement and synchronization motion of left ventricular myocardial longitudinal contraction in coronary artery disease

    ZHANG Shengguang,YU Jing,CHEN Ai,LUO Hede,HUANG Yunjian,WANG Rongjin,LIAO Heng (Department of Special Examination,the 98th Hospital PLA,Huzhou 313000, Zhejiang，China)

    [Abstract] Objective To evaluate the longitudinal myocardial displacement(Ds) and synchronization motion features of LV ontraction in coronary artery disease(CAD) using the tissue tracking (TT) and tissue synchronization imaging(TSI)Methods The LV apical long axis view,apical twochamber view and fourchamber view were obtained by TT and TSI in 20 CAD and 26 normal subjectsPeak systolic Ds and systolic time to peak(Ts)were measured and compared between the two groupsResults The abnormal segments detected by TT and TSI were consistent with coronary angiography and myocardial infarction in CAD groupDs was signiicantly lower in CAD group than that of the corresponding segments in normal subjects (P<005 or P<0001)Ts was delayed and the difference of Ts among segmentswas significantly increased in CAD patients (7148～182ms,P<005 or P<0001)Conclusion TT and TSI can more accurately evaluate the LV myocardial longitudinal contraction displacement and synchronization in CAD patients ...... 婵″倹鐏夐幃銊ユ躬娴ｈ法鏁ら幍瀣簚缁涘绁︾憴鍫熸閺冪姵纭堕弻銉ф箙閹存牔绗呮潪钘夊弿閺傚浄绱濋崣顖濆厴閺勵垵顫﹂幖婊呭偍瀵洘鎼告径杈╂埂閳ユ粏娴嗛惍浣测偓婵撶礉鐠囬鍋ｉ崙璇茬潌楠炴洘娓舵稉瀣煙閻ㄥ嫧鈧粎鏁搁懘鎴犲閳ユ繃鍨ㄩ垾婊冨斧缂冩垿銆夐垾婵婎問闂傤喓鈧拷


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