32例婴儿肝炎综合征临床分析(pdf)

    【摘要】 目的 探讨婴儿肝炎综合征的病因、临床表现及预后。方法 对确诊为婴儿肝炎综合征的32例病例资料进行临床观察及随访分析。结果 病原学检查结果提示病毒感染，尤其巨细胞包涵体病毒感染最多见，占59%，乙型肝炎病毒感染占第二位，为25%；巨细胞包涵体病毒感染可引起黄疸、肝肿大、肝功能异常以及胆道闭锁、溶血，且病情重，易致肝硬化，日后有可能引起智力及听力障碍等后遗症。结论 巨细胞包涵体病毒感染是婴儿肝炎综合征的主要病因。早发现、早诊断及早治疗是避免发展成为肝硬化、降低死亡率和减轻后遗症的关键。

    【关键词】 肝炎；巨细胞病毒；婴儿

    Clinical analysis of 32 cases with infant hepatitis syndrome

    JIN En-shun,LUO Jian-an.Department of Pediatrics,Liuhua Hospital of Shenzhen,Guangdong 518002,China

    【Abstract】 Objective To discuss the relations between the cause of infant hepatitis syndrome and clinical manifestation and prognosis.Methods 32 cases with infant hepatitis syndrome were clinically analyzed and follow-up survey was carried out.Results Virus infection,especially cytomegalovirus infection,59% played a key role and second infection of hepatitis B virus was 25%;The manifestations caused by cytomegalovirus were jaundice,abnormality of hepatic cell function,occlusion of biliary tract,hemolysis,cirrhosis and complications of mental retardation and hearing handicap.Conclusion Most of hepatitis syndrome was caused by cytomegalovirus,and early diagnosis and treatment are helpful in decreasing the mortality,preventing hepatic cirrhosis and lessening sequelae. ......