Alzhermer′s病患者胰岛素水平测定与对照分析
阿尔次海默病；胰岛素；胰岛素抵抗；血糖,,阿尔次海默病；胰岛素；胰岛素抵抗；血糖,1对象与方法,2结果,3讨论,参考文献
【摘要】 目的 探讨阿尔次海默病患者空腹血糖和空腹血浆胰岛素水平，以期发现胰岛素抵抗与阿尔次海默病的关系。 方法将2002年1月~2006年3月期间临床诊断为阿尔次海默病，且排除糖尿病的30例在院患者设为研究组，选取同期匹配的30名健康人为对照组，检测空腹血糖、空腹胰岛素、餐后2h血糖、餐后2h胰岛素，并进行比较。结果 研究组空腹胰岛素、HOMA胰岛素抵抗指数明显低于健康对照组，差异有极显著性(P<0.01)。空腹血糖、餐后2h血糖两组无显著性差异。 结论 阿尔次海默病患者的空腹胰岛素水平和HOMA胰岛素抵抗指数较低，未发现有胰岛素抵抗。【关键词】 阿尔次海默病；胰岛素；胰岛素抵抗；血糖
A controlled analysis on the level of insuline in the patients with Alzhermer’s disease
Yu Haiyan， Wang Qunsong
(Wuxi City Mental Health Center Wuxi,214151, Jiangsu, China)
【Abstract】 Objective To explore the bloodfasting glucose(BFS) and insuline levels in Alzheimer’s disease patients in order to find out the relation between insuline resistance and Alzheimer’s disease. Methods 30 Alzheimer’s disease patients without diabetes mellitus hospitalized during January in 2002 to March in 2006 as study group and 30 controllers were determined the bloodfasting glucose and insuline, blood glucose and insuline after 2 hours postmeal. The results were compared. Results The levels of empty-stomach insuline and HOMA insuline resistance index of the study group were significantly lower than those of the control group(P<0.01), the levels of BFS and 2 hours’ postprandial blood sugar were no obvious difference between the two groups. Conclusion The levels of BFS and HOMA insuline resistance index of Alzheimer’s disease patients are low, and there isn’t insuline resistance. ......
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