摘要:目的 研究胃腺癌(Gastric adenocarcinoma，GAC)神经组织浸润与临床病理学指标的关系。 方法 复习95例GAC组织常规切片，分析GAC的神经组织浸润与性别、年龄、组织学分化程度、肿瘤浸润深度、淋巴结转移、临床分期和肝、肺、卵巢转移等生物学行为的关系。 结果 95例GAC神经组织浸润的发生率为56%，神经组织浸润与肿瘤浸润深度、淋巴结转移和临床分期均呈正相关(P分别为0.000、0.010和0.004，r分别为0.492、0.265和0.293)，与性别、年龄、组织学分化程度和肝、肺、卵巢转移均无关(P>0.05)。 结论 GAC的神经组织浸润与肿瘤的浸润深度、淋巴结转移和临床分期等生物学行为有密切关系，提示发生神经组织浸润的GAC具有较强的浸润和转移能力。

    关键词:胃腺癌;病理学;神经浸润

    Clinical and pathological significance of neural invasion of gastric adenocarcinoma.

    WANG Lin，LI Hai-gang，ZENG Hong，et al.

    (Departmetn of Pathology of Affilaited Hospital of Sun Yan-sen Unversity，Guangzhou510120，Guangdong，P.R.China)

    Abstract:Objective To investigate the relationship between neural invasion and clinical pathological indexes in gastric adeno-carcinoma(GAC)patients. Methods 95GAC cases were reviewed.The relationship between neural invasion and clinical patho-logical indexes of GAC was analyzed. Results The neural invasion rate was56%(53/95)in GAC patients.The neural invasion rate was positively correlated with invasive depth ......