[摘要] 目的 调查肠易激综合征(IBS)150例患者的焦虑障碍，为心理治疗IBS提供依据。方法 以DSM-3为标准工具诊断焦虑障碍，焦虑自评量表评价其严重程度。将伴焦虑的IBS分为两组：对照组(常规内科治疗)，劳拉西泮组，随访8周，以IBS症状记分及焦虑自评量表积分减少50%或以上为治疗有效。结果 (1)150例IBS中48例诊断为焦虑障碍，其发生率为32%；(2)劳拉西泮组有效率为95.4%，其IBS症状分和焦虑自评量表积分明显下降，与对照组差异有显著性(P<0.001)；(3)劳拉西泮的不良反应较轻。结论 IBS伴随焦虑障碍的发病率较高，抗焦虑治疗能有效地改善焦虑和躯体症状。治疗宜首选苯二氮卓艹类药物。

    [关键词] 肠易激综合征；焦虑

    Anxiety in irritable bowel syndrome:A clinical study

    LIU Shi-ying，CHENG Xiang，YAN Qiu-li，et al.The Beijiao Hospital of Beijing，Beijing 102208，China

    [Abstract] Objective To determine the prevalence of anxiety in the patient with irritable bowel syndrome (IBS)，the clinical trial was conducted to compare the efficacy and the side effect between lorazepam and control group.Methods Anxiety disorder was diagnosed according to DSM-Ⅱ and the severity of anxiety disorder was evaluatd with the Self-Rating Anxiety scale (SAS).Thy patients was followed-up for 8 weeks.The treatment is effective when the score of IBS and SAS decrease to 50% or more.Results The prevalence of anxiety in IBS patients was 32%(48/150).The mean SAS scores and IBS scores were significantly improved after the treatment in lorazepam groups (P<0.001).There is less side effect in the lorazepam group.Conclusion The prevalence of anxiety disorder is higher in IBS patient.The antianxiety improve the anxiety and IBS effectively ......