复发性卵巢上皮癌二次减灭术意义及疗效影响因素
复发性上皮性卵巢癌;二次肿瘤细胞减灭术,,],复发性上皮性卵巢癌;二次肿瘤细胞减灭术,1资料与方法,2结果,3讨论,[参考文献]
[摘要] 目的: 探讨复发性卵巢上皮癌二次肿瘤细胞减灭术的意义及影响因素。 方法: 对85例复发性卵巢上皮癌进行回顾性临床病理资料及随访资料分析。 结果: 85例复发性卵巢上皮癌中,以存活≥3年为界,①58例行二次肿瘤细胞减灭术:32例浆液性囊腺癌中21例存活≥3年,22例高分化癌中18例存活≥3年,37例首次残余瘤<2cm中28例存活≥3年,24例两次手术间隔≥1年中19例存活≥3年,31例二次手术后残留2cm中25例存活≥3年,33例二次术后新化疗中27例存活≥3年;②27例未行二次手术中,21例单纯采用新化疗者9例存活≥3年,6例采用中药或放弃治疗者2例存活≥3年。 结论: 单纯二次肿瘤细胞减灭术对患者预后无积极意义,配合有效化疗药物的二次肿瘤细胞减灭术对提高患者生存率有积极意义;二次肿瘤细胞减灭术相关的影响因素为术后是否行有效化疗、首次与二次术后残余瘤大小、病理分级及两次手术间隔,其中最重要的为前三者,但与病理类型无关。[关键词] 复发性上皮性卵巢癌;二次肿瘤细胞减灭术
Significance of secondary cytoreductive surgery and influential factors in the treatment of patients with recurrent epithelial ovarian carcinoma
DING Hong ,LU Wen ,SUI Li-hua ,et al
(1.Naval Convalescent Home,Hangzhou Sanatorium,Nanjing Military District,Hangzhou310002,China;2.Second Affliated Hospital,Medical School of Zhejiang University,Hangzhou310009,China)
Abstract:Objective:To explore the significance and influential factors of secondary tumor cell surgery(STRS)in the treatment of patients with recurrent epithelial ovarian carcinoma.Methods:Retrospective analyses were made on85cases of clinical pathologic data and clinical follow-up sheets in patients with recurrent epithelial ovarian carcinoma.Results:3-year survival rate was consid-ered as standard in85patients.(1)58patients were administered STRS and such were the results.Of the32serous cystadeno-carcinoma ......
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