[摘要]目的 探讨人巨细胞病毒(HCMV)婴儿肝炎综合征的有效治疗方案。方法 选择2003～2005年住院的76例HCMV婴儿肝炎综合征病儿，随机分为两组。治疗组给予更昔洛韦(GCV)联合静脉用人血免疫球蛋白(IVIG)治疗;对照组单用GCV治疗。两组其他辅助治疗相同。结果 治疗组肝功能恢复及病毒载量下降均较对照组明显( t=2.334～3.580，P <0.05)。结论 GCV联合IVIG治疗HCMV婴儿肝炎综合征优于单用GCV。

    [关键词] 巨细胞病毒;婴儿;肝炎;更昔洛韦;免疫球蛋白类

    EFFECT OF GANCICLOVIR COMBINED WITH IVIG ON THE TREATMENT OF HCMV INFECTED INFANTILE HEPATITIS SYNDROME

    SONG YI-E， LIU HUA-LIN， LIU RUI-HAI

    (Department of Pharmacology， Pingyi People's Hospital， Pingyi 273300， China)

    [ABSTRACT]ObjectiveTo investigate the effective therapeutic protocol for infantile hepatitis syndrome (HIS) caused by human cytomegalovirus (HCMV). Methods Infants with infantile hepatitis syndrome caused by HCMV ( n =76) were divided into two groups. Treated group received ganciclovir (GCV) plus intravenous immunoglobulin (IVIG); control group received GCV only. ResultsThe patients in treated group had a better recovery of liver function and lower viral load than the patients in con-trol group ( t=2.334-3.580 ......