[摘要]目的 检测乙型肝炎(乙肝)病毒携带者血清转化生长因子α (TGF-α)的水平，探讨TGF-α检测的临床意义。方法 采用放射免疫分析法测定了90例乙肝病毒携带者血清TGF-α含量，并以30例正常者作为对照。结果 HBsAg(+)+HBeAg(+)+抗-HBc(+)组和HBsAg(+)+抗-HBe(+)+抗-HBc(+)组病人血清TGF-α含量均明显高于对照组，差异均有显著意义( F=6.864，q=5.657、4.912，P <0.01);HBsAg(+)+抗-HBc(+)组和HBsAg(+)组病人血清TGF-α含量与对照组比较，差异无统计学意义( q=1.516、0.397，P > 0.05 )。结论 血清TGF-α检测对乙肝病毒携带者的预后估计具有重要临床意义。

    [关键词] 转化生长因子α;肝炎病毒，乙型;放射免疫测定

    MEASUREMENT OF THE SERUM LEVELS OF TGF-alpha IN HBV-CARRIERS AND ITS CLINICAL SIGNIFICANCE

    WANG REN-PING， CAI ZHI-RONG， WANG WEI， et al

    (Health Examination Center of the Affiliated Hospital of Qingdao Unversi-ty Medical College， Qingdao 266003， China)

    [ABSTRACT]ObjectiveTo measure the serum levels of transforming growth factor-alpha (TGF-α) in HBV-carriers and discuss its clinical significance. MethodsHBV-carriers ( n =90) were divided into four groups: group Ⅰ with HBsAg(+) ......