蛇床子素；注射液；稳定性_____蛇床子素；注射液；稳定性

蛇床子素注射液的制备及稳定性考察

http://www.100md.com 《河北北方学院学报》 2006年第5期

蛇床子素；注射液；稳定性,,蛇床子素；注射液；稳定性,1材料与方法,2稳定性试验,3讨论,参考文献

     【摘要】目的：探讨蛇床子素注射液的处方及制备工艺并考察其稳定性。方法：采用紫外分光光度计测定注射液的含量，用初匀速法考察制剂在室温25℃下的贮存期和对强光的稳定性。结果：蛇床子素注射液对光稳定性较差，在25℃下蛇床子素注射液贮存期为198年。结论：本品制备方便，工艺可行，稳定性试验符合Arrhenius指数规律。

    【关键词】蛇床子素；注射液；稳定性

    Study on the Preparation and Stability of Osthol Injection

    GAO Yongrong，LI ZhanLin，SU Jun,et al

    The First Affiliated Hospital， Hebei North University，Zhangjiakou, 075000,Hebei,China；

    【ABSTRACT】 Objective: To study the preparation and stability of osthole injection. Methods:The UV method was used for the determination of content and prediction of expiry was studied by initial average rate methods at room temperature(25℃).The stability under stronglight was investigated as well. Results:The stability is poor under the condition of stronglight,the expiry term predicted at 25℃ is 198 year. Conclusion:The preparation procedure of the injection is simple, convenient. The stability test was in consistent with Arrhenius exponent rule and convenient.

    【KEY WORDS】 Osthole; Injection; Stability

    蛇床子为伞形科植物蛇床Cnidium monnieri(L.)Cuss.的干燥成熟果实 ......

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