皱皮木瓜总黄酮松弛胃肠平滑肌的效应机制
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柳 蔚, 杨兴海, 周 敏, 李从德
皱皮木瓜总黄酮;胃肠平滑肌;钙拮抗剂;乙酰胆碱柳蔚,杨兴海,周敏,李从德.皱皮木瓜总黄酮松弛胃肠平滑肌的效应机制. 世界华人消化杂志2007;15(2)165-167 FLC和Ver对高钾致家兔结肠带收缩的影响.2.2FLC对家兔空肠自律性收缩和Ach诱导收缩的影响[3]空肠
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柳蔚, 杨兴海, 三峡大学医学院药理教研室 湖北省宜昌市 443002
周敏, 李从德, 三峡大学医学院生理教研室 湖北省宜昌市 443002湖北省教育厅基金资助项目, No. 2004J001
通讯作者: 柳蔚, 443002, 湖北省宜昌市大学路8号, 三峡大学医学院药理教研室. liuwei_sxdx@163.com
电话: 0717-6397466
收稿日期: 2006-11-02 接受日期: 2006-11-21
Pharmacodynamical mechanisms of total flavonoids from Chaenomeles Lagenaria Koidz in the relaxation of gastrointestinal smooth muscles
Wei Liu, Xing-Hai Yang, Min Zhou, Cong-De Li
Wei Liu, Xing-Hai Yang, Department of Pharmacology, Medical College of Three Gorges University, Yichang 443002, Hubei Province, China
Min Zhou, Cong-De Li, Department of Physiology, Medical College of Three Gorges University, Yichang 443002, Hubei Province, China
Supported by the Fund from Education Department of Hubei Province, No. 2004J001
Correspondence to: Wei Liu, Department of Pharmacology, Medical College of Three Gorges University, 8 Daxue Road, Yichang 443002, Hubei Province,China. liuwei_sxdx@163.com
Received: 2006-11-02 Accepted: 2006-11-21
AbstractAIM: To elucidate the mechanisms of total flavonoids from Chaenomeles Lagenaria Koidz (FLC) in relaxing gastrointestinal smooth muscle.
METHODS: The relaxant effect of 2, 4 and 8 g/L FLC on the contraction induced by acetylcholine (ACh), high potassium chloride (KCl) and calcium chloride (CaCl2) in the isolated taenia coli, jejunum and ileum from rabbits ......
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