[摘要] 目的 研究术前用药对绝经期妇女宫颈扩张作用及对取环术的影响。方法 对160例绝经期取环术妇女随机分为两组各80例。研究组术前12 h口服米非司酮50 mg，对照组术前不服任何药物。分别观察两组宫颈软化及扩张情况、取环所用时间、失血量以及成功率。结果 研究组宫颈软化及扩张明显优于对照组(P<0.001)；取环成功率明显高于对照组(P<0.01)；手术时间、失血量及综合反应程度均明显低于对照组(P<0.05～0.01)。结论 术前应用药物利于宫颈软化及扩张，取环成功率高，痛苦小，方法简便安全，值得临床推广。

    [关键词] 药物；绝经；宫内节育器；米非司酮

    Clinical research of the application of drugs expand cervix uteri in taking intrauterine device from menopause women

    LIU Shi-ying，WANG Guang-hua，WANG Ying-yi.Department of Gynecology and Obstetrics，Shanghai Tenth People’s Hospital，Affiliated to Tongji University，Shanghai 200072，China

    [Abstract] Objective To research the effect of the application of drugs expand cervix uteri in taking intrauterine device (IUD) from menopause women.Methods 160 cases with menopause women were randomly divided into two group ......