倍他乐克治疗慢性充血性心衰的疗效观察 (pdf)

    【摘要】 目的 探讨β受体阻滞剂在慢性充血性心力衰竭中的疗效。方法 选择48例慢性充血性心力衰竭患者，在常规应用强心、利尿、扩血管药物的基础上，加用β受体阻滞剂倍它乐克。治疗2个月后观察心力衰竭患者心率、血压和心功能的变化，比较治疗前后上述指标的差异，以评估其临床疗效及安全性。结果 应用倍它乐克后心力衰竭患者心功能分级显著改善，心率明显降低(100.06±12.56 vs. 70.01±7.72,P<0.05)，收缩压及舒张压也显著降低。结论 在常规抗心力衰竭药物治疗基础上加用β受体阻滞剂可明显改善慢性心力衰竭患者的心功能，提高生活质量，延长患者寿命。

    【关键词】 倍他乐克； 充血性心力衰竭； 神经内分泌

    【Abstract】 Objective To investigate the effects of β blocker on chronic congestive heart failure. Methods Fourty eight patients with chronic congestive heart failure were selected. Βblocker of metoprolol was used on the base of routine therapy including digitalis, diuretics and vasodilators. Heart rate, blood pressure and cardiac function were observed and compared before and after treatment to evaluate its clinical effects and security. Results βblocker in addition to routine anti heart failure therapy could significantly improve cardiac functional class, reduce heart rate (100.06±12.56 vs. 70.01±7.72,P<0.05)and decrease systolic and diastolic blood pressure. Conclusion On the basis of routine anti heart failure drug therapy, βblocker could significantly improve cardiac function in patients with chronic heart failure, improve life quality and prolong life expectancy. ......