牛黄解毒多层片的研制
牛黄解毒片;,β-环糊精包合;,多层片;,HPLC,,牛黄解毒片;,β-环糊精包合;,多层片;,HPLC,1仪器与试药,2方法,3结果与讨论,参考文献:
摘要:目的以临床常用的中成药牛黄解毒片为基础,研究多层片的制备工艺,避免处方中挥发性成分冰片在制备、贮存过程中的损失。方法在实验中将冰片用β-环糊精包合压制内层片芯,其余七味药做外层包裹压制而成多层片。结果通过对包药率以及冰片含量的测定,确定了牛黄解毒多层片的生产工艺。结论β-环糊精包合技术可以减少冰片的损失。关键词:牛黄解毒片; β-环糊精包合; 多层片; HPLC
The Processing Method of Niuhuang Jiedu Mutilayer Tablet
TAO Lihua, LIU Fei
(Tonghua Normal College, Jilin,134002, China)
Abstract:ObjectiveBasing on the prescription of Niuhuang Jiedu Tablet, to study processing technology of its multilayer tablet, so as to induce the lose of borneol.MethodsBorneol was packed with βCyclodextrin pack matching as inside layer, rest seven flavor medicine were supressed as outside layer.ResultsMulti-layer precessing technology of Niuhuang Jiedu Tablet was established.ConclusionThe technology can reduce the lose of borneol.
Key words:Niuhuang Jiedu Tablet; βCyclodextrin; Multilayer tablet; HPLC
牛黄解毒片是由牛黄、大黄、黄芩、桔梗、石膏、雄黄、冰片、甘草8味中药组成的 ......
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