中乌头次碱制备工艺的研究
正交实验;,中乌头次碱;,制备工艺,,正交实验;,中乌头次碱;,制备工艺,1仪器与试剂,2方法,3结果,4讨论,参考文献:
摘要:目的研究中乌头次碱的制备工艺。方法采用四因素三水平的正交实验的方法,筛选最佳工艺条件,以多级质谱进行定性监测。结果以 pH=8,T=100℃,t=1.5 h,V=200 ml条件下所得中乌头次碱得量大。结论该制备工艺合理,适合工业化生产。关键词:正交实验; 中乌头次碱; 制备工艺
Study on the Preparing Technology of Hypacotine
LIU Yonggang, CHEN Yujuan,LIU Qian,SUN Yantong
(Pharmacy College of Jilin University, Changchun 130021, China)
Abstract:ObjectiveTo study the optimal preparing technology of Hypacotine.MethodsOrthogonal experiment was carried out to investigated 4 influentinal factors of pH ,T,t and V,and Hypacotine was identified by MSn.ResultsThe optimal process were:pH=8,T=100℃ ......
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