关键词 吉西他滨；顺铂；非小细胞肺癌；联合化疗

    摘要 目的 观察吉西他滨加顺铂联合化疗治疗非小细胞肺癌的近期疗效及毒副作用。方法 50例Ⅲb～Ⅳ期非小细胞肺癌，采用吉西他滨1 000mg/m2,静滴,d1、d8；顺铂30mg/m2,静滴,d2～d4,联合化疗。结果 50例中CR+PR 23例，有效率46%，主要毒副作用为骨髓抑制。结论 吉西他滨加顺铂联合化疗治疗晚期非小细胞肺癌疗效较好，毒副作用可耐受，值得临床推广应用。

    GEMCITABINE COMBINED CISPLATIN REGIMEN IN TREATMENT OF ADVANCED LUNG CANCER

    Bi Qingjun，Han Rui.

    The Fourth People's Hospital of Zibo,Zibo 255067,China

    Key words gemcitabine; cisplatin; advanced lung cancer; combined chemotherapy

    Abstract Objective To observe the near future effect of gemcitabine combined cisplatin regimen in the treatment of patients with advanced lung cancer. Methods 50 patients with advanced lung cancer were treated with GP regimen: GEM 1000mg/m, iv, d1~d8; DDP 30mg/m, iv, d2~d4. Results It showed that CR+PR 23,and overall response rate was 46%.The main effect was leukocytopenia. Conclusion Gemcitabine and cisplatin regimen show more better effect on advanced non-small cell lung cancer, furthermore its toxic reaction is tolerable.

    肺癌是严重危害人类健康和生命的恶性肿瘤 ......