关键词 心脏；恶性纤维组织细胞瘤；病理检查

    摘要 目的 报告1例罕见的心脏恶性纤维组织细胞瘤，结合文献复习，讨论心脏恶性纤维组织细胞瘤的临床病理特点。方法 通过组织学方法，对1例心脏恶性纤维组织细胞瘤的组织学形态进行观察，并进行了特染、免疫组织化学染色和电镜的研究。结果 患者左房内房间隔上可见一占位病变。体积10cm×3cm×9cm。显微镜下见肿瘤组织由梭形、卵圆形及多核细胞组成，异型性明显,核分裂多见。特殊染色：PAS(+)、AB(+)。免疫组化：CD68(+)、α-AT(±)、CEA(-)、KER(-)。电镜结果：瘤组织由多种细胞成分组成，以纤维母细胞为主。支持恶性纤维组织细胞瘤诊断。结论 原发心脏恶性纤维组织细胞瘤是一种非常罕见的心脏原发恶性肿瘤，具有一定的临床病理特点。

    CARDIAL MALIGNANT FIBROUS HISTIOCYTOMA:A REPORT OF 1 CASE

    Liu Qiaoling,Zhang Xiaohui,Yan Peisong,et al.

    Guangdong Foshan Nanhai Sanitation Vocation Education,Foshan 528200,China

    Key words heart； malignant fibrohistiocytoma; pathology check

    Abstract Objective To report 1 case with cardial malignant fibrohistiocytoma, and discuss its clinical pathological features based on literature review. Methods Histology features had been observed in the case with cardial malignant fibrohistiocytoma, and special staining, immunohistochemistry and electron microscope studies were also performed. Results The patient was a 42-year-old female, there was a tumor with volume of 10×3×9cm in interauricular septum of the left atrium. The tumor was consisted of spindle, oval and polynucleate cells, with an obvious atypia and many mitosis figures. Special staining showed negative for PAS and alcian blue. Immunohistochemistry results were CD68(+),α-AT(±),CEA(-),KER(-). Electron microscophs revealed that the tumor was consisted of various cells including fibroblast, which indicated a diagnosis of malignant fibrohistiocytoma. Conclusion Primary malignant histiocytoma is rare in heart which contains clinical pathological characteristics. ......