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支气管动脉灌注治疗中晚期肺癌40例疗效分析
http://www.100md.com 《实用医技杂志》 2006年第13期
肺癌;支气管动脉;治疗,,],肺癌;支气管动脉;治疗,1材料和方法,2结果,3讨论,参考文献:
     [摘要] 目的:评价支气管动脉灌注(bronchial arterial infusion,BAI)化疗药物治疗中晚期肺癌的疗效及安全性。方法:对40例中晚期肺癌患者行支气管动脉插管,通过支气管动脉灌注化疗药物。采用顺铂(DDP)50 mg~60 mg或卡铂(CBP)300 mg~500 mg、丝裂霉素(MMC)10 mg和阿霉素(ADM)50 mg三联药物,40例共行88次BAI治疗。结果:40例患者中完全缓解(CR)4例,部分缓解(PR)24例,稳定(SD)9例,进展(PD)3例,有效率(CR+PR)为70.0%,1 a生存率为62.5%。鳞癌和富血供肺癌的BAI疗效分别优于腺癌和乏血供者(P<0.01)。结论:支气管动脉灌注治疗中晚期肺癌安全有效。

    [关键词] 肺癌;支气管动脉;治疗

    The Evaluation of Bronchial Arterial Infusion Chemotherapy Effect on Midadvanced Lung Cancer

    HOU Wenzhong,YU Zhao,QIU Weijiang

    (Meizhou People's Hosipital,Meizhou,Guangdong 514031, China)

    Abstract:Objective clinical chemotherapy effect and safety of bronchial arterial infusion (BAI) in the midadvanced lung cancer.Methods Forty patients of midadvanced lung cancer confirmed by pathologhy received BAI treatment.In the combination of chemotherapy medicine,they were DDP (50 mg~60 mg) or CBP (300 mg~500 mg),MMC (10 mg) and ADM (50 mg).There were total 88 BAI in 40 patients.Results In 40 patients,there were 4 cases of complete response ......

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