【摘 要】 目的 观察脂调康胶囊对高脂血症患者血清肿瘤坏死因子-α(TNF-α)的影响。 方法 采用随机、单盲、阳性药平行对照方法将186例高脂血症患者分成2组，治疗组124例，对照组62例。治疗组用脂调康胶囊，对照组用脂必妥片。测定2组治疗前后TNF-α的变化。 结果 2组治疗后血清TNF-α均较治疗前显著降低(P<0.001);而治疗后2组间比较，治疗组血清TNF-α降低较对照组有显著性差异(P<0.05)。 结论 脂调康胶囊通过降低TNF-α含量，减轻其对机体的损伤，防止动脉粥样硬化等疾病的形成。

    【关键词】 脂调康胶囊;高脂血症;肿瘤坏死因子-α

    Effect of Zhitiaokang capsule on tumor necrosis factor-αin serum of patients with hyperlipidemia YANG Muxiang ，TIANYuanxiang，LIU Jiandong，et al.

    College of TCM of Hebei Medical University，Hebei，Shijiazhuang 050091，China

    【Abstract】 Objective To observe the effect of Zhitiaokang capsule on tumor necrosis factor-α(TNF-α)in se-rum of patients with hyperlipidemia.Methods 186patients with hyperlipidemia were divided into two groups by ran-domized，single-blinded and positive drug controlled methods.124patients in treatment group were treated by Zhitiao-kang capsule，62patients in control group were treated by Zhibituo tablets.The change of TNF-αin serum for both groups was detected.Results The TNF-αwas significantly decreased after treatment ......