老年糖尿病周围神经病变的相关危险因素研究
糖尿病周围神经病变;,危险因素;,老年人,,糖尿病周围神经病变;,危险因素;,老年人,1对象与方法,2结果,3讨论,[参考文献]
【摘要】 目的 探讨老年糖尿病周围神经病变(diabetic peripheral neuropathy,DNP)的相关危险因素。 方法 将89例老年糖尿病患者按是否合并周围神经病变分为病变组与对照组,观察2组体质量指数(BMI)、腰臀比(WHR)、糖化血红蛋白(HbA1c)、三酰甘油(TG)、总胆固醇(TC),高密度脂蛋白胆固醇(HDLC)、低密度脂蛋白胆固醇(LDLC)及末梢神经功能、下肢血管超声等指标并进行比较分析。 结果 病变组WHR、LDLC、下肢血管损伤程度均较对照组升高(P<005),神经传导速度、HDLC较对照组降低(P<005),多元回归分析提示DNP与HbA1c、LDLC、TG、血管病变负相关,与HDLC正相关。 结论 DNP的发生与血糖、血脂及血管病变有关。【关键词】 糖尿病周围神经病变; 危险因素; 老年人
Study on correlated risk factors of diabetic peripheral neuropathy in elderly patients
ZUO Wenbiao,WANG Ning,ZHANG Chunxiang,QIAN Chunping.
Department of endocrinology,the 97th Hospital of PLA ,Xuzhou 221004,China
【Abstract】 Objective To investigate the relevant risk factors in elderly diabetic peripheral neuropathy. Methods Eightynine cases of elderly diabetic patients were divided into two groups: one group with diabetic peripheral neuropathy (n=39),and another without diabetic peripheral neuropathy(n=50),body mass index(BMI),waist to hip rate(WHR),glycosylated hemoglobin(HbA1c),triglycerides total cholesterol(TC) ......
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