【摘要】 目的 探讨慢性乙型肝病及肝源性溃疡与幽门螺杆菌(Helicobacter pylori，Hp)感染的关系。 方法 慢性乙型肝炎患者342例，乙型肝炎后肝硬化患者298例，非慢性肝病患者229例，均行抗Hp-IgG抗体血清学检测及快速尿素酶试验。 结果 慢性乙型肝炎、乙型肝炎后肝硬化及非慢性肝病对照组的Hp感染率分别为51.5%、45.0%和72.9%。肝源性溃疡Hp感染率为46.3%，而对照组消化性溃疡Hp阳性率为82.1%。 结论 慢性乙型肝病患者的Hp感染率与对照组相比较低，Hp感染不是肝源性溃疡发生的重要原因。

    【关键词】 幽门螺杆菌；乙型肝炎；肝硬化；消化性溃疡

    Hepatitis B virus-related chronic liver disease,hepatogenic ulcer and Helicobacter pylori infection

    ZHANG Qiou-yin,HUA Jian-ping,LI Jun-mei.The First Central Hospital,Tianjin 300192,China

    【Abstract】 Objective To investigate the role of Helicobacter pylori (H.pylori ) infection in patients with hepatitis B virus-related chronic liver disease and hepatogenic ulcer. Methods 342 patients with chronic hepatitis B and 298 liver cirrhosis were studied. 229 age-matched individuals with no evidence of hepatitis B virus (HBV) infection or liver diseases served as control. Serum samples from these groups were tested for specific IgG antibodies to H.pylori ......