依达拉奉结合早期康复治疗急性脑梗死60例疗效观察
依达拉奉;,脑梗死;,老年人,【主题词】依达拉奉;脑梗死;老年人,1对象和方法,2结果,3讨论,参考文献
【摘要】 目的 评价依达拉奉注射液治疗急性脑梗死(ACI)的疗效。 方法 采用随机对照试验,选择发病 48 h内的急性脑梗死患者120例,随机分为依达拉奉组(60例)及对照组(60例)。治疗前及治疗后1月对患者进行神经功能缺损(national institute of health stroke scale,NIHSS)评分、FuglMeyer评分或Barthel指数比较作为主要疗效判断标准。 结果 治疗后 30 d依达拉奉组NIHSS评分(371±243)较对照组(786±365)降低明显,差异具有统计学意义(P<005)。治疗 30 d后,2组患者的FuglMeyer评分及Barthel指数均明显提高,但依达拉奉组提高幅度明显大于对照组。表明依达拉奉组患者的神经功能缺损恢复程度优于对照组。 结论 依达拉奉是一种治疗急性缺血性脑卒中有效的神经保护剂。【主题词】 依达拉奉; 脑梗死; 老年人
Effects of edaravone and early rehabilitation on acute cerebral infarction
LI Guohui,CHEN Hui.
Department of Neurology,Zhongshan Chinese Medical Hospital,Zhongshan 528400 China
【Abstract】 Objective To investigate the effects of edaravone on acute cerebral infarction(ACI). Methods A randomized,controlled study was performed.One hundred and sixty patients,who had an onset of ACI within 48 hours,were allocated to edaravone group(n=60)or the control group(n=60)randomly.Before treatment and 30 days after treatment,the neurological deficits(NIHSS),FuglMeyer and Barthel index were evaluated. Resukts There were significant differences between edaravone group(371±243)and the control group(786±365).Thirty days after treatment the improvement of FuglMeyer and Barthel index was significant.The improvement of Edaravone group was more significant than that of the control group. Conckusions Edaravone is a new effective neuroprotective agent in treating ACI. ......
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