脑梗死与循环免疫复合物的相关性研究 (pdf)

    【摘要】 目的 探讨循环免疫复合物与脑梗死的关系。方法 采用酶联免疫吸附试验(ELISA)方法测定脑梗死患者血中巨细胞病毒抗体(CMV-IgG与CMV-IgM)及衣原体抗体(CP-IgG)，并与健康对照组比较。结果 脑梗死组循环免疫复合物显著升高(P﹤0.01)，其中CMV-IgM在发病早期明显升高(P﹤0.01)，随着病情康复，其水平逐渐下降。CMV-IgG和CP-IgG也呈现类似变化。结论 脑梗死患者血中CMV-IgG、CMV-IgM和CD-IgG升高，循环复合物对脑梗死的发生有一定的不良影响。

    【关键词】 脑梗死；巨细胞病毒抗体IgG、IgM；衣原体抗体IgG；循环免疫复合物

    The study of the relationship between the cerebral infaction and the circulating immune complexes

    SUN Hong-chun,ZHUO Wen-yan,HUANG Cui-zhen,et al.Department of the Neurology The People’s Hospital,Zhuhai 519000,China

    【Abstract】 Objective To explore the relationship between the circulating immune complexes (CIC) and the cerebral infarction.Methods Serum anti-cytomegalovirus antibodies ( CMV-IgG and CMV-IgM ) and anti-Chlamydia pneumonia antibody ( CP-IgG ) in 140 cases were determinated by ELISA. The results were compared with the control group.Results The circulating immune complexes (CIC ) in the cerebral infarction group was increased. The anti-cytomegalovirus antibodies were increased significantly in the early stage. There was significantly difference between cerebral infarction group and the control group ( P﹤0.01 ). But the CIC at late stage were reduced in the cerebral infarction group( P﹤0.01 ). And the CMV-IgM and CP-IgG were so.Conclusion The CMV-IgG and IgM and CP-IgG were increased in cerebral infarction patients.The increased total CIC may accelerate the disease. ......