老年退行性心瓣膜病变与颈动脉粥样硬化相关性分析
心瓣膜疾病；,颈动脉疾病；,超声检查,多普勒,彩色；,老年人,1对象与方法,2结果,3讨论,参考文献
【摘要】 目的 探讨老年人群中退行性心瓣膜病变(SDHVD)与颈动脉粥样硬化(CAS)高发生率之间存在的密切关系。 方法 随机抽取老年患者139例，年龄60~93岁，平均(7904±755)岁，按年龄分3组进行心脏和颈动脉超声检查，观测不同年龄组SDHVD和CAS发生情况，再以心脏彩超结果区分为阳性组(有SDHVD)和阴性组(无SDHVD)，比较不同组别CAS发生率，并探讨高血压、2型糖尿病、冠心病、脑梗死不同病种SDHVD及CAS发生情况。 结果 SDHVD、CAS发病率随增龄而增加，组间差异明显；SDHVD患者颈动脉斑块阳性符合率很高，SDHVD阳性组斑块发生率大于阴性组(P< 005)，SDHVD与CAS存在密切相关性。 结论 SDHVD的发生率与CAS的发生率存在明显的相关性，CAS的发生率与心脑血管病的发生发展密切相关，超声检测退行性心瓣膜病变可提示CAS可能性，SDHVD阳性老年人及时行颈动脉超声是有必要的，对冠心病、脑卒中的流行病学研究及早期预防诊断治疗都具有重要理论意义和现实意义。【主题词】 心瓣膜疾病； 颈动脉疾病； 超声检查，多普勒，彩色； 老年人
Relationship between senile degenerative heart valve disease and carotid atherosclerosis ZHANG Tao,ZHU Siping,LU Xiaowei,GAO Yongdong. Department of Geriatrics, the First Affiliated Hospital of Nanjing Medical University,Nanjing 210029 China
【Abstract】 Objective To investigate the relationship between senile degenerative heart valve disease(SDHVD) and carotid atherosclerosis(CAS) in elderly patients. Methods Heart and carotid sonography examination were undertaken on 139 randomly collected subjects(mean age， 7904±755 years) in 3 groups divided by age to investigate the occurrence of SDHVD and CAS. CAS occurrence rate of SDHVD positive group and SDHVD negative group was compared and the correlations between SDHVD/CAS and hypertension,diabetes mellitus,cerebral infarction were investigated. Resukts The incidences of SDHVD and CAS were increased by age.The incidence of carotid plaques in SDHVD positive group was higher than that in SDHVD negative group(P<005). Conckusions There is significant correlation between the incidences of SDHVD and CAS. Carotid sonography is necessary for SDHVD positive patients. ......
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