胃痛立应软胶囊；_提取工艺；_高良姜素_

胃痛立应软胶囊制备中二氧化碳超临界流体萃取后的提取工艺研究

http://www.100md.com 《时珍国医国药》 2005年第12期

胃痛立应软胶囊；,提取工艺；,高良姜素,,胃痛立应软胶囊；,提取工艺；,高良姜素,1材料,2方法与结果,3讨论,参考文献：

     摘要：目的：研究胃痛立应软胶囊制备中二氧化碳超临界流体(SFECO2)萃取后药材的提取工艺。方法：对比乙醇回流、温浸、超声及水煎等提取工艺，以溶媒浓度、用量、提取时间为研究因素，经正交设计进行提取工艺条件的优选。结果：最佳提取工艺路线为10倍量75%乙醇回流提取1次，提取时间为1.5 h。结论：以高良姜素提取率为指标，该最佳提取工艺能充分提取药材中的有效成分。

    关键词：胃痛立应软胶囊；提取工艺；高良姜素

    Study on Extraction in the Processes of Weitongliying Soft Capsule after Extracted by Supercritical Carbon Dioxide Fluid

    FU Haizhen，JIA Xiaobin，YANG Zhonglin，XIA Guohua，XIN Huaisheng

    (School of Pharmacy，Jiangsu University,Zhenjiang,212001；China； Academy of TCM of Jiangsu, Nanjing 210028；China；School of Traditional Chinese Medicines，China Pharmaceutical University，Nanjing 210038，China)

    Abstract:Objective:To study the extraction in the processes of Weitongliying Soft Capsule after extracted by Supercritical carbon dioxide fluid.Methods:The most appropriate technology was screened based on the comparative study among the technology of ethanol circumfluence,ultrasonic extraction,water warm immersion and water decoction ......

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