【摘要】 目的 观察灯盏花素对老年不稳定心绞痛的临床疗效和血液生化指标的影响。方法 给予不稳定心绞痛治疗组的86例患者用灯盏花素20ml静脉滴注14天，并设对照组60例。观察两组的临床疗效及对血液流变学的影响。结果 灯盏花素组临床总有效率为86.0%，对照组为66.7%,两组比较差异有显著性(P<0.01)。灯盏花素组治疗后全血粘度、血浆粘度、红细胞比积及纤维蛋白原与治疗前比较均显著下降(P<0.01或P<0.05)，其血液流变学改善程度明显优于对照组。结论 注射用灯盏花素是一种治疗不稳定心绞痛的有效药物，可抑制不稳定心绞痛的发作。

    【关键词】 灯盏花素 ；老年人；不稳定心绞痛

    【Abstract】 Objective To observe the influences of Breviscapine injection on the clinical therapeutic effect and hemorrheology in treating aged patients of unstable angina pectoris (UAP). Methods The cases with unstable angina pectoris were randomly divided into treatment group (86 cases) and control group (60cases). The treatment group were treated with 20ml of Breviscapine injection through intravenous drip for 14 days. The clinical therapeutic effect and the change of hemorrheologic characteristics were observed. Results The total effective rate was 86.0% in Breviscapine group and 66.7% in control group. The difference between the two groups was significant (P<0.01). In Breviscapine group , the high and low shear whole blood viscosity,plasma viscosity, hematocrit and fibrinogen was lower after the treatment (P<0.01 or P<0.05).The improvement of hemorheology characteristics in Breviscapine group was more obvious than that in control group. Conclusion Breviscapine injection is a kind of effective drug in treating patients of UAP ,so it could inhibit the break out of UAP. ......